Roasted Garlic Chicken Penne

Featured in: Snack Time Heroes

This classic Italian-American dish combines al dente penne pasta with tender roasted chicken breasts, all enveloped in a luxurious oven-roasted garlic cream sauce. Whole garlic cloves are slowly roasted until golden and soft, then mashed into a silky beurre blanc-style sauce made with butter, flour, milk, and heavy cream. The roasted garlic becomes mellow and sweet, infusing the sauce with deep, aromatic flavor. Ready in just 50 minutes, this elegant yet comforting main course serves four and pairs beautifully with crisp white wine.

Updated on Tue, 20 Jan 2026 13:17:00 GMT
Golden roasted garlic chicken penne pasta in a creamy sauce garnished with fresh parsley and Parmesan cheese.  Save
Golden roasted garlic chicken penne pasta in a creamy sauce garnished with fresh parsley and Parmesan cheese. | collationspot.com

The kitchen filled with that unmistakable roasted garlic aroma while my roommate kept poking her head in, asking if dinner was ready yet. I'd been experimenting with garlic cream sauces for months, but something about roasting the garlic first changed everything. That night, the way the silky sauce coated every penne curve made it instantly clear this recipe was staying. Now it's the most requested dish at every dinner party.

Last winter my sister came over exhausted from work, and I made this while she curled up on the couch. She took one bite and actually stopped talking mid-sentence. That's when I knew this wasn't just another pasta dish, it was comfort food that demands attention.

Ingredients

  • 2 large boneless, skinless chicken breasts: I pound them slightly to even thickness so they cook through without drying out at the edges
  • 340 g (12 oz) penne pasta: The ridges catch sauce perfectly, but rigatoni works if that's what you have in the pantry
  • 1 large head garlic: Choose heads with tight papery skins and no green sprouts peeking out, those make the garlic bitter
  • 1 tsp olive oil: Just enough to coat the garlic before roasting, helps those cloves caramelize beautifully
  • 2 tbsp unsalted butter: Start the roux with cold butter so it melts slowly into the flour without browning too fast
  • 2 tbsp all-purpose flour: This thickens the cream sauce into something velvety that coats pasta rather than pooling at the bottom
  • 400 ml (1 2/3 cups) whole milk: Room temperature milk incorporates into the roux smoothly without making lumps
  • 120 ml (1/2 cup) heavy cream: The secret to restaurant-style richness without needing any strange ingredients
  • 60 g (2 oz) grated Parmesan cheese: Freshly grated melts into the sauce, pre-grated sometimes has anti-caking agents that make it gritty
  • 1/2 tsp salt and 1/4 tsp freshly ground black pepper: Season the sauce before adding pasta, it's harder to adjust afterward
  • 1/4 tsp crushed red pepper flakes: Optional, but I love the subtle heat that cuts through all that cream
  • 2 tbsp chopped fresh parsley: Adds a bright fresh finish and makes the dish look like it came from a restaurant kitchen

Instructions

Product image
Organize kitchen cleaning supplies and cooking essentials on the wall to keep prep areas tidy and accessible.
Check price on Amazon
Roast the garlic to golden perfection:
Preheat your oven to 200°C (400°F), slice the top off that garlic head to expose all the cloves, drizzle with olive oil, wrap tightly in foil, and let it roast for 30 minutes until soft and golden.
Cook the chicken while garlic roasts:
Season chicken breasts generously with salt and pepper, place on a baking sheet, and roast alongside the garlic for 22 to 25 minutes until juices run clear or internal temperature hits 74°C (165°F).
Rest and slice the chicken:
Let the chicken rest for 5 minutes so juices redistribute, then slice thinly against the grain for tender bite-sized pieces.
Cook pasta to al dente perfection:
Boil penne in generously salted water according to package directions, drain when still slightly firm to the bite, and reserve 120 ml (1/2 cup) of that starchy pasta water before draining completely.
Prep the roasted garlic paste:
Squeeze those soft roasted cloves right out of their skins, mash them into a smooth paste with a fork, and breathe in that incredible aroma.
Build the cream sauce base:
Melt butter in a large skillet over medium heat, whisk in flour and cook for 1 minute until bubbly, then gradually whisk in room temperature milk and cream, stirring constantly for 3 to 4 minutes until thickened.
Finish the sauce with roasted garlic:
Stir in that mashed roasted garlic, Parmesan, salt, pepper, and red pepper flakes, cook until cheese melts completely and sauce becomes silky smooth.
Bring everything together:
Add sliced chicken and cooked penne to the sauce, toss gently to coat every piece, and add reserved pasta water if sauce needs thinning.
Serve with generous garnishes:
Plate immediately while hot, sprinkled with fresh parsley and extra Parmesan because there's no such thing as too much cheese on pasta.
Product image
Organize kitchen cleaning supplies and cooking essentials on the wall to keep prep areas tidy and accessible.
Check price on Amazon
A close-up of roasted garlic chicken penne with a rich, velvety sauce and freshly grated Parmesan.  Save
A close-up of roasted garlic chicken penne with a rich, velvety sauce and freshly grated Parmesan. | collationspot.com

My friend's husband usually hates creamy pasta dishes but went back for thirds. Watching someone completely change their mind about food they thought they didn't like, that's the magic of a really good recipe.

Make It Yours

Sometimes I throw in sautéed mushrooms or spinach during step 7 when the sauce is finishing. The mushrooms add earthy depth while spinach brings fresh color and nutrients. Both options turn this into a more complete one-bowl meal.

Perfect Wine Pairing

A crisp Pinot Grigio cuts through the cream beautifully without overwhelming the garlic. Light Chardonnay works too, but anything too oaky fights with the delicate roasted flavors. Keep it chilled and pour a glass while the chicken roasts.

Storage and Reheating

This keeps remarkably well in the refrigerator for up to 3 days, stored in an airtight container. Reheat gently with a splash of milk to bring the sauce back to life, and it tastes just as good as the first night.

  • Freeze individual portions without the parsley garnish for up to 2 months
  • Thaw overnight in the refrigerator before reheating slowly on the stovetop
  • Add fresh parsley after reheating so it stays bright and doesn't wilt
Product image
Effortlessly chop vegetables, slice meats, and prep ingredients smoothly for everyday cooking and recipe preparation.
Check price on Amazon
Roasted garlic chicken penne served in a warm bowl, paired with a crisp white wine and crusty bread. Save
Roasted garlic chicken penne served in a warm bowl, paired with a crisp white wine and crusty bread. | collationspot.com

There's something deeply satisfying about a recipe that transforms simple ingredients into something restaurant-worthy. This pasta has saved countless weeknight dinners and impressed more dinner guests than I can count.

Recipe Help

Can I prepare the roasted garlic ahead of time?

Yes, roast the garlic up to 2 days in advance. Store it in an airtight container in the refrigerator. Simply reheat gently before mashing into the sauce, or use it cold—it will warm through as the sauce cooks.

How do I know when the chicken is fully cooked?

The internal temperature should reach 74°C (165°F) when measured with a meat thermometer inserted into the thickest part. The juices should run clear. Let it rest for a few minutes before slicing to retain moisture.

What can I use if I don't have heavy cream?

Substitute with whole milk, but reduce it by simmering to concentrate the flavor. Alternatively, use crème fraîche, sour cream, or a combination of milk with a touch of butter for richness.

How do I fix a sauce that's too thick?

Gradually whisk in reserved pasta water, whole milk, or cream one tablespoon at a time until you reach the desired consistency. The starch in pasta water also helps the sauce cling nicely to the penne.

Can I make this dish gluten-free?

Absolutely. Use gluten-free penne pasta and substitute the all-purpose flour with cornstarch, rice flour, or a commercial gluten-free flour blend in equal amounts. Always verify that all ingredients, especially the pasta, are certified gluten-free.

What wine pairs best with this dish?

Crisp, light-bodied white wines work beautifully. Try Pinot Grigio, Chardonnay, or Vermentino. The acidity cuts through the richness of the cream sauce while complementing the roasted garlic's depth.

Roasted Garlic Chicken Penne

Tender penne with roasted chicken and silky garlic cream sauce. Rich, aromatic, and deeply satisfying.

Prep Time
15 min
Time to Cook
35 min
Overall Time
50 min
Created by Chloe Martin


Skill Level Medium

Cuisine Type Italian-American

Makes 4 Portions

Special Diets None specified

What You’ll Need

Proteins

01 2 large boneless, skinless chicken breasts (14 oz)

Pasta

01 12 oz penne pasta

Roasted Garlic

01 1 large head garlic
02 1 teaspoon olive oil

Cream Sauce

01 2 tablespoons unsalted butter
02 2 tablespoons all-purpose flour
03 1 2/3 cups whole milk
04 1/2 cup heavy cream
05 2 oz grated Parmesan cheese
06 1/2 teaspoon salt
07 1/4 teaspoon freshly ground black pepper
08 1/4 teaspoon crushed red pepper flakes, optional

Garnish

01 2 tablespoons chopped fresh parsley
02 Extra grated Parmesan cheese, to serve

How-To

Step 01

Preheat oven: Preheat oven to 400°F

Step 02

Prepare garlic for roasting: Slice the top off the head of garlic to expose the cloves. Drizzle with 1 teaspoon olive oil and wrap in foil. Roast for 30 minutes until soft and golden

Step 03

Roast chicken: Season chicken breasts with salt and pepper. Place on a baking sheet and roast alongside garlic for 22 to 25 minutes, or until juices run clear and internal temperature reaches 165°F. Let rest, then slice thinly

Step 04

Cook pasta: Cook penne in salted boiling water according to package instructions until al dente. Drain and set aside, reserving 1/2 cup pasta water

Step 05

Process roasted garlic: Squeeze roasted garlic cloves from their skins and mash to a paste

Step 06

Create cream sauce base: In a large skillet, melt butter over medium heat. Whisk in flour and cook for 1 minute. Gradually whisk in milk and cream, stirring constantly until thickened, about 3 to 4 minutes

Step 07

Finish sauce: Stir in mashed roasted garlic, Parmesan, salt, pepper, and red pepper flakes if using. Cook until cheese is melted and sauce is smooth

Step 08

Combine components: Add sliced chicken and cooked penne to the sauce. Toss to coat, adding reserved pasta water as needed for desired consistency

Step 09

Serve: Serve immediately, garnished with fresh parsley and extra Parmesan

Gear Needed

  • Chef's knife
  • Baking sheet
  • Aluminum foil
  • Large pot
  • Colander
  • Large skillet
  • Whisk

Allergy Details

Review every item for allergens and connect with your healthcare provider if you’re unsure.
  • Contains wheat (gluten)
  • Contains milk (dairy)
  • May contain eggs in some pasta brands

Nutrition Breakdown (each serving)

Info for reference only—don’t take this as expert medical guidance.
  • Caloric Value: 670
  • Lipids: 24 g
  • Carbohydrates: 72 g
  • Proteins: 41 g